Brief Information of the Compound and Protein
Compound Name
5-(4-chlorophenyl)-3-[(2,4-difluorophenyl)carbonyl]-2-(2,3-dimethoxyphenyl)-2,3-dihydro-1,3,4-thiadiazole
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PubChem ID
CID: 23648540
Canonical SMILES
COc1cccc(C2SC(=NN2C(=O)c2ccc(F)cc2F)c2ccc(Cl)cc2)c1OC
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Compound Formula C23H17ClF2N2O3S
Compound Structure
Protein Name
Oxysterols receptor LXR-alpha
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group H
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Nuclear hormone receptor subfamily 1 group H member 3
Uniprot ID
Q13133
Gene Name
NR1H3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
EC50 = 6700 nM
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