Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-(4-amino-3-methoxy-phenyl)-7-morpholin-4-yl-5,10-dihydro-dibenzo[b,e][1,4]diazepin-11-one
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 PubChem ID
CID: 44427515
Canonical SMILES
COc1cc(ccc1N)-c1ccc2c(Nc3cc(ccc3NC2=O)N2CCOCC2)c1
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Compound Formula C24H24N4O3
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase Chk1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CAMK protein kinase group
>
CAMK protein kinase CAMK1 family
>
CAMK protein kinase CHK1 subfamily
Uniprot ID
O14757
Gene Name
CHEK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 2100 nM
   TI
   LI
   LO
   TS
2
EC50 = 46100 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4 nM