Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-(3-methoxy-4-nitrophenyl)-8-(2-oxopyrrolidin-1-yl)-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one
    Show/Hide
 PubChem ID
CID: 44427513
Canonical SMILES
COc1cc(ccc1N)-c1ccc2c(Nc3ccc(cc3NC2=O)N2CCCC2=O)c1
    Show/Hide
Compound Formula C24H22N4O3
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase Chk1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CAMK protein kinase group
>
CAMK protein kinase CAMK1 family
>
CAMK protein kinase CHK1 subfamily
Uniprot ID
O14757
Gene Name
CHEK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
2
EC50 = 49500 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4 nM