Brief Information of the Compound and Protein
Compound Name
N-(Aryl)-thiazole-5-carboxamide 17
    Show/Hide
PubChem ID
CID: 23644841
Canonical SMILES
FC(F)(Cl)Oc1ccc(NC(=O)c2scnc2CCc2ccncc2)cc1
    Show/Hide
Compound Formula C18H14ClF2N3O2S
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 85 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 110 nM