Brief Information of the Compound and Protein
Compound Name
N-(Aryl)-thiazole-5-carboxamide 27
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PubChem ID
CID: 23644850
Canonical SMILES
FC(F)(F)c1cc(NC(=O)c2scnc2CCc2ccncc2)ccc1Cl
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Compound Formula C18H13ClF3N3OS
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 190 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 270 nM