Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(4-tert-Butyl-benzyl)-3-isoquinolin-5-yl-urea
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 PubChem ID
CID: 9819027
SID: 14777619
Canonical SMILES
CC(C)(C)c1ccc(CNC(=O)Nc2cccc3cnccc23)cc1
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Compound Formula C21H23N3O
Compound Structure
Protein Name
 Protein Info 
Transient receptor potential cation channel subfamily V member 1
Protein Classification
Ion channel
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Voltage-gated ion channel
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Transient receptor potential channel
Uniprot ID
Q8NER1
Gene Name
TRPV1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 3 nM
   TI
   LI
   LO
   TS
2
Ki = 0.3 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 13.8 nM