Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-Isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea
    Show/Hide
 PubChem ID
CID: 8068410
SID: 14952509
Canonical SMILES
FC(F)(F)c1ccc(CNC(=O)Nc2cccc3cnccc23)cc1
    Show/Hide
Compound Formula C18H14F3N3O
Compound Structure
Protein Name
 Protein Info 
Transient receptor potential cation channel subfamily V member 1
Protein Classification
Ion channel
>
Voltage-gated ion channel
>
Transient receptor potential channel
Uniprot ID
Q8NER1
Gene Name
TRPV1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 3 nM
   TI
   LI
   LO
   TS
2
Ki = 5 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4 nM
2 Ki = 18.3 nM