Brief Information of the Compound and Protein
Compound Name
4-[({4-[(5-chloro-2H-1,3-benzodioxol-4-yl)amino]-6-methoxyquinazolin-7-yl}oxy)methyl]pyridine-2-carbonitrile
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PubChem ID
CID: 5330198
SID: 15203072
Canonical SMILES
COc1cc2c(Nc3c4OCOc4ccc3Cl)ncnc2cc1OCc1ccnc(c1)C#N
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Compound Formula C23H16ClN5O4
Compound Structure
Protein Name
Proto-oncogene tyrosine-protein kinase Src
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Src family
Uniprot ID
P12931
Gene Name
SRC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 90 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 10 nM