Brief Information of the Compound and Protein
Compound Name
(2R)-2-[[5-[(2,3-difluorophenyl)methylsulfanyl]-2-(methylamino)-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]propan-1-ol
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PubChem ID
CID: 44431195
Canonical SMILES
CNc1nc2nc(SCc3cccc(F)c3F)nc(N[C@H](C)CO)c2s1
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Compound Formula C16H17F2N5OS2
Compound Structure
Protein Name
C-X-C chemokine receptor type 2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CXC chemokine receptor
Uniprot ID
P25025
Gene Name
CXCR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 7.943 nM
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   LI
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