Brief Information of the Compound and Protein
Compound Name
 Compound Info 
Telomestatin (TMS)
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 PubChem ID
CID: 443590
SID: 14911415
Canonical SMILES
Cc1oc2nc1-c1nc(c(C)o1)-c1nc(co1)-c1nc(co1)-c1nc(co1)-c1nc(co1)-c1nc(co1)C1=NC2CS1
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Compound Formula C26H14N8O7S
Compound Structure
Protein Name
 Protein Info 
Telomerase reverse transcriptase
Protein Classification
Enzyme
>
Transferase
Uniprot ID
O14746
Gene Name
TERT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  5
1
IC50 = 0.64 nM
   TI
   LI
   LO
   TS
2
IC50 = 0.7 nM
   TI
   LI
   LO
   TS
3
IC50 = 58 nM
   TI
   LI
   LO
   TS
4
IC50 = 900 nM
   TI
   LI
   LO
   TS
5
IC50 = 1150 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.7 nM
2 IC50 = 20 nM