Brief Information of the Compound and Protein
Compound Name
 Compound Info 
9-[4-(N,N-dimethylamino)phenylamino]-3,6-bis(3-pyrrolodinopropionamido) acridine
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 PubChem ID
CID: 9808666
SID: 14764772
Canonical SMILES
CN(C)c1ccc(Nc2c3ccc(NC(=O)CCN4CCCC4)cc3nc3cc(NC(=O)CCN4CCCC4)ccc23)cc1
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Compound Formula C35H43N7O2
Compound Structure
Protein Name
 Protein Info 
Telomerase reverse transcriptase
Protein Classification
Enzyme
>
Transferase
Uniprot ID
O14746
Gene Name
TERT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 90 nM
   TI
   LI
   LO
   TS
CL000072 A2780
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 113 nM
   TI
   LI
   LO
   TS
2
IC50 = 100 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  3
1
IC50 = 45 nM
   TI
   LI
   LO
   TS
2
IC50 = 65 nM
   TI
   LI
   LO
   TS
3
IC50 = 830 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 113 nM
2 EC50 = 115 nM
3 EC50 = 120 nM
4 EC50 = 6300 nM
5 IC50 = 5400 nM