Brief Information of the Compound and Protein
Compound Name
4-((bis(cyclohexylmethyl)amino)methyl)-N-(naphthalen-1-yl)thiazol-2-amine
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PubChem ID
CID: 11496063
SID: 16597973
Canonical SMILES
C(C1CCCCC1)N(CC1CCCCC1)Cc1csc(Nc2cccc3ccccc23)n1
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Compound Formula C28H37N3S
Compound Structure
Protein Name
C-C chemokine receptor type 4
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CC chemokine receptor
Uniprot ID
P51679
Gene Name
CCR4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000108 CCRF-CEM Homo sapiens (Human)  3
1
IC50 = 18 nM
   TI
   LI
   LO
   TS
2
IC50 = 31 nM
   TI
   LI
   LO
   TS
3
IC50 = 530 nM
   TI
   LI
   LO
   TS