Brief Information of the Compound and Protein
Compound Name
3-(4'-chloro-biphenyl-4-yl)-4-cyano-5-ethyl-1-methyl-1H-pyrrole-2-carboxylic acid
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PubChem ID
CID: 44417062
Canonical SMILES
CCc1c(C#N)c(c(C(O)=O)n1C)-c1ccc(cc1)-c1ccc(Cl)cc1
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Compound Formula C21H17ClN2O2
Compound Structure
Protein Name
Glutamate receptor 2
Protein Classification
Ion channel
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Ligand-gated ion channel
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Ionotropic glutamate receptor
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AMPA receptor
Uniprot ID
P42262
Gene Name
GRIA2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 142 nM
   TI
   LI
   LO
   TS
2
EC50 = 984 nM
   TI
   LI
   LO
   TS