Brief Information of the Compound and Protein
Compound Name
4-cyano-3-(3'-cyano-biphenyl-4-yl)-5-ethyl-1-methyl-1H-pyrrole-2-carboxylic acid
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PubChem ID
CID: 44416892
Canonical SMILES
CCc1c(C#N)c(c(C(O)=O)n1C)-c1ccc(cc1)-c1cccc(c1)C#N
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Compound Formula C22H17N3O2
Compound Structure
Protein Name
Glutamate receptor 2
Protein Classification
Ion channel
>
Ligand-gated ion channel
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Ionotropic glutamate receptor
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AMPA receptor
Uniprot ID
P42262
Gene Name
GRIA2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 395 nM
   TI
   LI
   LO
   TS
2
EC50 = 974 nM
   TI
   LI
   LO
   TS