Brief Information of the Compound and Protein
Compound Name
3-(2'-chloro-biphenyl-4-yl)-4-cyano-5-ethyl-1-methyl-1H-pyrrole-2-carboxylic acid
    Show/Hide
PubChem ID
CID: 44417082
Canonical SMILES
CCc1c(C#N)c(c(C(O)=O)n1C)-c1ccc(cc1)-c1ccccc1Cl
    Show/Hide
Compound Formula C21H17ClN2O2
Compound Structure
Protein Name
Glutamate receptor 4
Protein Classification
Ion channel
>
Ligand-gated ion channel
>
Ionotropic glutamate receptor
>
AMPA receptor
Uniprot ID
P48058
Gene Name
GRIA4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 157 nM
   TI
   LI
   LO
   TS
2
EC50 = 225 nM
   TI
   LI
   LO
   TS