Brief Information of the Compound and Protein
Compound Name
3-(4-tert-butylphenyl)-4-cyano-5-(methylthio)thiophene-2-carboxylic acid
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PubChem ID
CID: 16046205
SID: 24432274
Canonical SMILES
CSc1sc(C(O)=O)c(c1C#N)-c1ccc(cc1)C(C)(C)C
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Compound Formula C17H17NO2S2
Compound Structure
Protein Name
Glutamate receptor 4
Protein Classification
Ion channel
>
Ligand-gated ion channel
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Ionotropic glutamate receptor
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AMPA receptor
Uniprot ID
P48058
Gene Name
GRIA4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  3
1
EC50 = 214 nM
   TI
   LI
   LO
   TS
2
EC50 = 1558 nM
   TI
   LI
   LO
   TS
3
EC50 = 1559 nM
   TI
   LI
   LO
   TS