Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-(4-tert-butylphenyl)-4-cyano-5-(dimethylamino)thiophene-2-carboxylic acid
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 PubChem ID
CID: 44416681
Canonical SMILES
CN(C)c1sc(C(O)=O)c(c1C#N)-c1ccc(cc1)C(C)(C)C
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Compound Formula C18H20N2O2S
Compound Structure
Protein Name
 Protein Info 
Glutamate receptor 2
Protein Classification
Ion channel
>
Ligand-gated ion channel
>
Ionotropic glutamate receptor
>
AMPA receptor
Uniprot ID
P42262
Gene Name
GRIA2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 176 nM
   TI
   LI
   LO
   TS
2
EC50 = 2854 nM
   TI
   LI
   LO
   TS