Brief Information of the Compound and Protein
Compound Name
3-biphenyl-4-yl-4-cyano-5-methylsulfanyl-thiophene-2-carboxylic acid
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PubChem ID
CID: 44416520
Canonical SMILES
CSc1sc(C(O)=O)c(c1C#N)-c1ccc(cc1)-c1ccccc1
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Compound Formula C19H13NO2S2
Compound Structure
Protein Name
Glutamate receptor 4
Protein Classification
Ion channel
>
Ligand-gated ion channel
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Ionotropic glutamate receptor
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AMPA receptor
Uniprot ID
P48058
Gene Name
GRIA4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 795 nM
   TI
   LI
   LO
   TS
2
EC50 > 3000 nM
   TI
   LI
   LO
   TS