Brief Information of the Compound and Protein
Compound Name
2-phenyl-1-{4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}-1,2,3,4-tetrahydroisoquinolin-6-ol
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PubChem ID
CID: 9953602
SID: 14929063
Canonical SMILES
Oc1ccc2C(N(CCc2c1)c1ccccc1)c1ccc(OCCN2CCCC2)cc1
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Compound Formula C27H30N2O2
Compound Structure
Protein Name
Estrogen receptor
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group A
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Nuclear hormone receptor subfamily 3 group A member 1
Uniprot ID
P03372
Gene Name
ESR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
IC50 = 11.5 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 10.69 nM
2 IC50 = 10.7 nM
3 IC50 = 20.99 nM
4 IC50 = 21 nM