Brief Information of the Compound and Protein
Compound Name
(HEPT) 1-(2-Hydroxy-ethoxymethyl)-5-methyl-6-phenylsulfanyl-1H-pyrimidine-2,4-dione
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PubChem ID
CID: 64993
SID: 15271995
Canonical SMILES
Cc1c(Sc2ccccc2)n(COCCO)c(=O)[nH]c1=O
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Compound Formula C14H16N2O4S
Compound Structure
Protein Name
Reverse transcriptase/RNaseH
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
Q72547
Gene Name
POL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000247 MT-4 Homo sapiens (Human)  1
1
IC50 = 5060 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 7000 nM
2 IC50 = 17000 nM
3 IC50 > 6000 nM