Brief Information of the Compound and Protein
Compound Name
2-[5-[(1R)-1-[3-cyclopropyloxy-4-(difluoromethoxy)phenyl]-2-(1-oxidopyridin-1-ium-3-yl)ethyl]-1,3-thiazol-2-yl]-1,1,1,3,3,3-hexafluoropropan-2-ol
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PubChem ID
CID: 11017241
SID: 16078923
Canonical SMILES
OC(c1ncc(s1)[C@H](Cc1ccc[n+]([O-])c1)c1ccc(OC(F)F)c(OC2CC2)c1)(C(F)(F)F)C(F)(F)F
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Compound Formula C23H18F8N2O4S
Compound Structure
Protein Name
3',5'-cyclic-AMP phosphodiesterase 4A
Protein Classification
Enzyme
>
Phosphodiesterase
>
Phosphodiesterase 4
>
Phosphodiesterase 4A
Uniprot ID
P27815
Gene Name
PDE4A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 48 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 56 nM