Brief Information of the Compound and Protein
Compound Name
3-(5-bromopyridin-2-yl)-1-[2-(pyridin-2-yl)ethyl]thiourea hydrochloride
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PubChem ID
CID: 3000870
SID: 14753507
Canonical SMILES
Brc1ccc(NC(=S)NCCc2ccccn2)nc1
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Compound Formula C13H13BrN4S
Compound Structure
Protein Name
Reverse transcriptase/RNaseH
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
Q72547
Gene Name
POL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000247 MT-4 Homo sapiens (Human)  1
1
EC50 = 20 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 15 nM
2 IC50 = 430 nM
3 IC50 = 600 nM
4 IC50 = 700 nM
5 IC50 = 800 nM
6 IC50 = 1030 nM
7 IC50 = 1060 nM
8 IC50 = 2500 nM
9 IC50 = 3200 nM
10 IC50 = 4200 nM
11 Ki = 600 nM