Brief Information of the Compound and Protein
Compound Name
3-biphenyl-4-ylethynyl-5-methyl-[1,2,4]triazine
    Show/Hide
PubChem ID
CID: 16735659
SID: 26693836
Canonical SMILES
Cc1cnnc(n1)C#Cc1ccc(cc1)-c1ccccc1
    Show/Hide
Compound Formula C18H13N3
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
IC50 = 510 nM
   TI
   LI
   LO
   TS