Brief Information of the Compound and Protein
Compound Name
BX-517
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PubChem ID
CID: 11161844
SID: 16241196
Canonical SMILES
C\C(=C1\C(=O)Nc2ccc(NC(N)=O)cc12)c1ccc[nH]1
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Compound Formula C15H14N4O2
Compound Structure
Protein Name
3-phosphoinositide-dependent protein kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase PDK1 subfamily
Uniprot ID
O15530
Gene Name
PDPK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000048 PC-3 Homo sapiens (Human)  1
1
IC50 = 100 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 5 nM
2 IC50 = 6 nM
3 IC50 = 9 nM