Brief Information of the Compound and Protein
Compound Name
1-[5-(4-amino-8,9-dihydro-7H-pyrimido[4,5-b][1,4]diazepin-6-yl)-2-methylphenyl]-3-[3-(trifluoromethyl)phenyl]urea
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PubChem ID
CID: 15941390
SID: 22392799
Canonical SMILES
Cc1ccc(cc1NC(=O)Nc1cccc(c1)C(F)(F)F)C1=Nc2c(N)ncnc2NCC1
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Compound Formula C22H20F3N7O
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase VEGFR family
Uniprot ID
P35918
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 52 nM
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