Brief Information of the Compound and Protein
Compound Name
 Compound Info 
propan-2-yl (4R)-2-[[(2,5-difluorophenyl)methylamino]methyl]-4-sulfanylpyrrolidine-1-carboxylate
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 PubChem ID
CID: 44400838
Canonical SMILES
CC(C)OC(=O)N1C[C@H](S)CC1CNCc1cc(F)ccc1F
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Compound Formula C16H22F2N2O2S
Compound Structure
Protein Name
 Protein Info 
Endothelin-converting enzyme 1
Protein Classification
Enzyme
>
Protease
>
Metallo protease
>
Metallo protease MAE clan
>
Metallo protease M13 family
Uniprot ID
P42892
Gene Name
ECE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000031 MDCK
 Cell Line Info 
Canis lupus familiaris (Dog)  1
1
IC50 = 1090 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 16 nM