Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2S,4R)-4-Acetylsulfanyl-2-(2,4,5-trifluoro-benzyloxymethyl)-pyrrolidine-1-carboxylic acid 2,3-dihydro-benzo[1,4]dioxin-5-yl ester
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 PubChem ID
CID: 10141595
SID: 15132808
Canonical SMILES
CC(=O)S[C@@H]1C[C@@H](COCc2cc(F)c(F)cc2F)N(C1)C(=O)Oc1cccc2OCCOc12
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Compound Formula C23H22F3NO6S
Compound Structure
Protein Name
 Protein Info 
Endothelin-converting enzyme 1
Protein Classification
Enzyme
>
Protease
>
Metallo protease
>
Metallo protease MAE clan
>
Metallo protease M13 family
Uniprot ID
P42892
Gene Name
ECE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000031 MDCK
 Cell Line Info 
Canis lupus familiaris (Dog)  1
1
IC50 = 76.5 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 6.9 nM