Brief Information of the Compound and Protein
Compound Name
(2S,4R)-4-Mercapto-2-(2,4,5-trifluoro-benzyloxymethyl)-pyrrolidine-1-carboxylic acid 2-methoxycarbonyl-phenyl ester
    Show/Hide
PubChem ID
CID: 131255
SID: 15093413
Canonical SMILES
O=c1cc(oc2ccccc12)N1CCOCC1
    Show/Hide
Compound Formula C13H13NO3
Compound Structure
Protein Name
Endothelin-converting enzyme 1
Protein Classification
Enzyme
>
Protease
>
Metallo protease
>
Metallo protease MAE clan
>
Metallo protease M13 family
Uniprot ID
P42892
Gene Name
ECE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000031 MDCK Canis lupus familiaris (Dog)  1
1
IC50 = 67 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 12 nM