Brief Information of the Compound and Protein
Compound Name
(R)-6-tert-butyl-2-(2-methyl-4-(3-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-1H-benzo[d]imidazole
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PubChem ID
CID: 44447973
Canonical SMILES
C[C@@H]1CN(CCN1c1nc2ccc(cc2[nH]1)C(C)(C)C)c1ncccc1C(F)(F)F
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Compound Formula C22H26F3N5
Compound Structure
Protein Name
Transient receptor potential cation channel subfamily V member 1
Protein Classification
Ion channel
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Voltage-gated ion channel
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Transient receptor potential channel
Uniprot ID
Q8NER1
Gene Name
TRPV1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 32.4 nM
   TI
   LI
   LO
   TS
2
IC50 = 1778 nM
   TI
   LI
   LO
   TS