Brief Information of the Compound and Protein
Compound Name
N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-2-[(4-methylbenzoyl)amino]benzamide
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PubChem ID
CID: 22004473
Canonical SMILES
COc1cc2CCN(CCc3ccc(NC(=O)c4ccccc4NC(=O)c4ccc(C)cc4)cc3)Cc2cc1OC
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Compound Formula C34H35N3O4
Compound Structure
Protein Name
ATP-dependent translocase ABCB1
Protein Classification
Transporter
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Primary active transporter
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ATP-binding cassette
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ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000072 A2780 Homo sapiens (Human)  2
1
IC50 = 524.81 nM
   TI
   LI
   LO
   TS
2
IC50 = 691.83 nM
   TI
   LI
   LO
   TS