Brief Information of the Compound and Protein
Compound Name
N-[2-[[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]carbamoyl]phenyl]-3,4-dimethoxybenzamide
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PubChem ID
CID: 11957988
SID: 17406131
Canonical SMILES
COc1ccc(cc1OC)C(=O)Nc1ccccc1C(=O)Nc1ccc(CCN2CCc3cc(OC)c(OC)cc3C2)cc1
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Compound Formula C35H37N3O6
Compound Structure
Protein Name
ATP-dependent translocase ABCB1
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000072 A2780 Homo sapiens (Human)  2
1
IC50 = 331.13 nM
   TI
   LI
   LO
   TS
2
IC50 = 338.84 nM
   TI
   LI
   LO
   TS
CL000135 A2780ADR Homo sapiens (Human)  1
1
IC50 = 338.84 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 331.13 nM