Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2-enamide
    Show/Hide
 PubChem ID
CID: 6918638
SID: 14899204
Canonical SMILES
ONC(=O)\C=C\c1cccc(c1)S(=O)(=O)Nc1ccccc1
    Show/Hide
Compound Formula C15H14N2O4S
Compound Structure
Protein Name
 Protein Info 
Histone deacetylase 1
Protein Classification
Epigenetic regulator
>
Eraser
>
Histone deacetylase
>
HDAC class I
Uniprot ID
Q13547
Gene Name
HDAC1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 18 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.376 nM
2 IC50 = 15 nM
3 IC50 = 20 nM
4 IC50 = 34 nM
5 IC50 = 63 nM
6 Ki = 0.85 nM
7 Ki = 0.9 nM
8 Ki = 26 nM