Brief Information of the Compound and Protein
Compound Name
methyl 2-[1'-(cyclooctylmethyl)-2-oxospiro[indole-3,4'-piperidine]-1-yl]acetate
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PubChem ID
CID: 44404679
Canonical SMILES
COC(=O)CN1C(=O)C2(CCN(CC3CCCCCCC3)CC2)c2ccccc12
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Compound Formula C24H34N2O3
Compound Structure
Protein Name
Kappa-type opioid receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Opioid receptor
Uniprot ID
P41145
Gene Name
OPRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 640 nM
   TI
   LI
   LO
   TS