Brief Information of the Compound and Protein
Compound Name
2-Benzyl-4-(5-fluoro-2-hydroxy-phenyl)-2-hydroxy-4-methyl-pentanoic acid (1-oxo-1,3-dihydro-isobenzofuran-5-yl)-amide
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PubChem ID
CID: 10238624
SID: 15240544
Canonical SMILES
CC(C)(CC(O)(Cc1ccccc1)C(=O)Nc1ccc2C(=O)OCc2c1)c1cc(F)ccc1O
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Compound Formula C27H26FNO5
Compound Structure
Protein Name
Glucocorticoid receptor
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  1
1
EC50 = 420 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 60 nM