Brief Information of the Compound and Protein
Compound Name
1-(3-{1-[1-(1-Methylcyclooctyl)piperidin-4-yl]-1H-benzimidazol-2-yl}phenyl)methanamine
    Show/Hide
PubChem ID
CID: 25207950
SID: 57415016
Canonical SMILES
CC1(CCCCCCC1)N1CCC(CC1)n1c(nc2ccccc12)-c1cccc(CN)c1
    Show/Hide
Compound Formula C28H38N4
Compound Structure
Protein Name
Kappa-type opioid receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Opioid receptor
Uniprot ID
P41145
Gene Name
OPRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 154 nM
   TI
   LI
   LO
   TS
2
Ki = 72 nM
   TI
   LI
   LO
   TS