Brief Information of the Compound and Protein
Compound Name
 Compound Info 
BMCL186218 Compound 1
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 PubChem ID
CID: 25190510
Canonical SMILES
CN(C(=O)c1ccccc1)c1ccc2n(CCC(N)=O)c(NC(=O)c3cccs3)nc2c1
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Compound Formula C23H21N5O3S
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase ITK/TSK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Tec family
Uniprot ID
Q08881
Gene Name
ITK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000302 DT40
 Cell Line Info 
Gallus gallus (Chicken)  2
1
IC50 = 2400 nM
   TI
   LI
   LO
   TS
2
IC50 = 2700 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 14 nM
2 IC50 = 25 nM
3 IC50 = 58 nM