Brief Information of the Compound and Protein
Compound Name
(R)-7-chloro-10-methyl-1,3,4,10b-tetrahydropyrazino[2,1-a]-isoindol-6(2H)-one
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PubChem ID
CID: 16115392
Canonical SMILES
Cc1ccc(Cl)c2C(=O)N3CCNC[C@H]3c12
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Compound Formula C12H13ClN2O
Compound Structure
Protein Name
5-hydroxytryptamine receptor 2B
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P41595
Gene Name
HTR2B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000065 HEK293-EBNA Homo sapiens (Human)  2
1
EC50 = 290 nM
   TI
   LI
   LO
   TS
2
Ki = 730 nM
   TI
   LI
   LO
   TS