Brief Information of the Compound and Protein
Compound Name
(R)-7-chloro-9-ethyl-1,3,4,10b-tetrahydropyrazino[2,1-a]-isoindol-6(2H)-one
    Show/Hide
PubChem ID
CID: 11483068
Canonical SMILES
CCc1cc2[C@@H]3CNCCN3C(=O)c2c(Cl)c1
    Show/Hide
Compound Formula C13H15ClN2O
Compound Structure
Protein Name
5-hydroxytryptamine receptor 2C
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P28335
Gene Name
HTR2C
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000065 HEK293-EBNA Homo sapiens (Human)  2
1
EC50 = 49 nM
   TI
   LI
   LO
   TS
2
Ki = 124 nM
   TI
   LI
   LO
   TS