Brief Information of the Compound and Protein
Compound Name
3-(1-Morpholin-2-yl-1H-indazol-3-yl)-4-[1-(1,4,4a,8a-tetrahydro-naphthalen-2-yl)-1H-indol-3-yl]-pyrrole-2,5-dione
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PubChem ID
CID: 10144909
SID: 15136088
Canonical SMILES
O=C1NC(=O)C(=C1c1cn(-c2ccc3ccccc3c2)c2ccccc12)c1nn(CCCN2CCOCC2)c2ccccc12
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Compound Formula C36H31N5O3
Compound Structure
Protein Name
Protein kinase C beta type
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase PKC family
>
AGC protein kinase PKC alpha subfamily
Uniprot ID
P05771
Gene Name
PRKCB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 72 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 18 nM
2 IC50 = 190 nM