Brief Information of the Compound and Protein
Compound Name
3-[1-(3-Dimethylamino-propyl)-1H-indazol-3-yl]-4-[1-(1,4,4a,8a-tetrahydro-naphthalen-1-yl)-1H-indol-3-yl]-pyrrole-2,5-dione
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PubChem ID
CID: 10143584
SID: 15134769
Canonical SMILES
CN(C)CCCn1nc(C2=C(C(=O)NC2=O)c2cn(-c3cccc4ccccc34)c3ccccc23)c2ccccc12
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Compound Formula C34H29N5O2
Compound Structure
Protein Name
Protein kinase C beta type
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase PKC family
>
AGC protein kinase PKC alpha subfamily
Uniprot ID
P05771
Gene Name
PRKCB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 600 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 29 nM
2 IC50 = 87 nM