Brief Information of the Compound and Protein
Compound Name
4-Oxo-1-[3-(1-oxy-pyridin-3-ylethynyl)-phenyl]-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid cyclopropylamide
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PubChem ID
CID: 9919680
SID: 14904905
Canonical SMILES
[O-][n+]1cccc(c1)C#Cc1cccc(c1)-n1cc(C(=O)NC2CC2)c(=O)c2cccnc12
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Compound Formula C25H18N4O3
Compound Structure
Protein Name
3',5'-cyclic-AMP phosphodiesterase 4A
Protein Classification
Enzyme
>
Phosphodiesterase
>
Phosphodiesterase 4
>
Phosphodiesterase 4A
Uniprot ID
P27815
Gene Name
PDE4A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 6.7 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 5.1 nM