Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(4aS)-1-(4-fluorophenyl)-4a-methyl-6-[4-(trifluoromethyl)phenyl]sulfonyl-4,5,7,8-tetrahydropyrazolo[3,4-g]isoquinoline
    Show/Hide
 PubChem ID
CID: 44454870
Canonical SMILES
C[C@@]12CN(CCC1=Cc1c(C2)cnn1-c1ccc(F)cc1)S(=O)(=O)c1ccc(cc1)C(F)(F)F
    Show/Hide
Compound Formula C24H21F4N3O2S
Compound Structure
Protein Name
 Protein Info 
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000229 SW1353
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 78 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 3.4 nM