Brief Information of the Compound and Protein
Compound Name
1-(4-fluorophenyl)-4a-[(4-fluorophenyl)methyl]-6-methylsulfonyl-4,5,7,8-tetrahydropyrazolo[3,4-g]isoquinoline
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PubChem ID
CID: 11547009
SID: 16649171
Canonical SMILES
CS(=O)(=O)N1CCC2=Cc3c(CC2(Cc2ccc(F)cc2)C1)cnn3-c1ccc(F)cc1
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Compound Formula C24H23F2N3O2S
Compound Structure
Protein Name
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000229 SW1353 Homo sapiens (Human)  1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 13 nM