Brief Information of the Compound and Protein
Compound Name
1-(4-fluorophenyl)-4a-[(4-fluorophenyl)methyl]-6-(pyridin-2-ylmethyl)-4,5,7,8-tetrahydropyrazolo[3,4-g]isoquinoline
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PubChem ID
CID: 11561826
SID: 16664038
Canonical SMILES
Fc1ccc(CC23CN(Cc4ccccn4)CCC2=Cc2c(C3)cnn2-c2ccc(F)cc2)cc1
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Compound Formula C29H26F2N4
Compound Structure
Protein Name
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000229 SW1353 Homo sapiens (Human)  1
1
Ki = 390 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 18 nM