Brief Information of the Compound and Protein
Compound Name
methyl 2-[(2,3-difluorophenyl)methylsulfanyl]-4-[[(2R)-1-hydroxypropan-2-yl]amino]-7-oxo-8H-pteridine-6-carboxylate
    Show/Hide
PubChem ID
CID: 44454985
Canonical SMILES
COC(=O)c1nc2c(N[C@H](C)CO)nc(SCc3cccc(F)c3F)nc2[nH]c1=O
    Show/Hide
Compound Formula C18H17F2N5O4S
Compound Structure
Protein Name
C-X-C chemokine receptor type 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor
>
CXC chemokine receptor
Uniprot ID
P25025
Gene Name
CXCR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 2 nM
   TI
   LI
   LO
   TS