Brief Information of the Compound and Protein
Compound Name
1'-(4-tert-butylcyclohexyl)-2-methyl-2,3-dihydro-1H-spiro[isoquinoline-4,4'-piperidine]-3-one
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PubChem ID
CID: 24776398
Canonical SMILES
CN1Cc2ccccc2C2(CCN(CC2)C2CCC(CC2)C(C)(C)C)C1=O
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Compound Formula C24H36N2O
Compound Structure
Protein Name
Kappa-type opioid receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Opioid receptor
Uniprot ID
P41145
Gene Name
OPRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 178 nM
   TI
   LI
   LO
   TS