Brief Information of the Compound and Protein
Compound Name
(R)-N,N-dimethyl-2-(4-(1-(thiazol-4-ylmethyl)-1H-indazol-5-ylamino)quinazolin-5-yloxy)propanamide
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PubChem ID
CID: 16117347
SID: 24764520
Canonical SMILES
C[C@@H](Oc1cccc2ncnc(Nc3ccc4n(Cc5cscn5)ncc4c3)c12)C(=O)N(C)C
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Compound Formula C24H23N7O2S
Compound Structure
Protein Name
Receptor tyrosine-protein kinase erbB-2
Protein Classification
Enzyme
>
Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase EGFR family
Uniprot ID
P04626
Gene Name
ERBB2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000083 MCF-7 Homo sapiens (Human)  1
1
IC50 = 230 nM
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