Brief Information of the Compound and Protein
Compound Name
2-(4-Ethylpiperazin-1-yl)-5-{[6-methoxy-7-(2-methoxyethoxy)quinazolin-4-yl]amino}benzo-1,4-quinone
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PubChem ID
CID: 11648430
SID: 16751822
Canonical SMILES
CCN1CCN(CC1)C1=CC(=O)C(Nc2ncnc3cc(OCCOC)c(OC)cc23)=CC1=O
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Compound Formula C24H29N5O5
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 133 nM
2 IC50 = 270.6 nM