Brief Information of the Compound and Protein
Compound Name
2-[[6-methoxy-7-(2-methoxyethoxy)quinazolin-4-yl]amino]-5-(2,2,2-trifluoro-1-phenylethoxy)cyclohexa-2,5-diene-1,4-dione
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PubChem ID
CID: 11656638
SID: 16760137
Canonical SMILES
COCCOc1cc2ncnc(NC3=CC(=O)C(OC(c4ccccc4)C(F)(F)F)=CC3=O)c2cc1OC
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Compound Formula C26H22F3N3O6
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4.6 nM
2 IC50 = 365.9 nM