Brief Information of the Compound and Protein
Compound Name
2-(dimethylamino)-5-[[6-methoxy-7-(2-methoxyethoxy)quinazolin-4-yl]amino]cyclohexa-2,5-diene-1,4-dione
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PubChem ID
CID: 11509519
SID: 16611449
Canonical SMILES
COCCOc1cc2ncnc(NC3=CC(=O)C(=CC3=O)N(C)C)c2cc1OC
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Compound Formula C20H22N4O5
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 31 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1144.1 nM
2 IC50 = 5000.3 nM